Research
Research within the IHU reConnect is organized into 7 main themes, which meet 4 objectives:
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Bringing together the stakeholders of hearing health
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Intensifying innovation and entrepreneurship
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Moving from compensatory medicine to restorative medicine
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Meeting the medical, societal, educational requirements raised by hearing and speech disorders
10 research teams
Cognition and communication
hearing
Dirigée par Luc Arnal & Diane Lazard
Neural code in the auditory system
Directed by Jérémie Barral
Dynamics of the auditory system and multisensory perception
Directed by Brice Bathellier
Clinical and translational exploration of auditory synaptopathies
Directed by Didier Dulon & Hung Thai-Van
Neural code in the auditory system
Directed by Jérémie Barral
Neural code in the auditory system
Directed by Jérémie Barral
Our workpackages
Workpackage 1
New Treatments and handling of sudden and fluctuating deafness
Based on a complete clinical and biological assessment of sudden and fluctuating deafness recruited from ENT emergencies in Ile-de-France, WP1 aims to identify biomarkers of the pathologies involved (traumatic, inflammatory, microvascular, pressure-related, etc.), in order to target appropriate therapies.
Workpackage 2
Preventing and treating progressive hearing loss
The aim is to develop innovative care pathways addressing the variable effectiveness of prosthetic treatments for sensorineural hearing loss. To achieve this, they encompass various approaches of gene therapy, pharmacological treatments, optogenetic cochlear implants, molecular biomarker diagnostics, and robot-based surgery.
Workpackage 3
Characterizing and treating Auditory Perception Disorders
Functional hearing disorders (tinnitus, hyperacusis and misophonia) are common and often disabling. Their pathophysiological mechanisms are poorly understood, and their treatment unsatisfactory. WP3 aims to improve understanding of their causes, diagnosis and treatment.
Workpackage 4
Hearing and dementia: from disease mechanisms to treatment
Hearing and auditory dysfunctions in dementia have been overlooked although progressive hearing loss stands out as the first potentially modifiable risk factor of this condition. WP4 proposes to characterize the role of hearing in dementia in order to improve prevention, diagnosis, and treatment.
Workpackage 5
Rewiring disrupted audio-phonological networks
WP5 will deploy evidence-based therapy for disorders of the audio-phonological loop in 5 areas: neuroplasticity in acquired deafness, phonemic representations in dyslexia, synchronization of speech reception in autism, syllabification in stuttering, restoring speech communication with BCI.
Workpackage 6
Network and data science
This workpackage aims to advance technologies for the diagnosis and treatment of hearing impairments through AI and data science. This includes developing AI tools for hearing aid operation, image analysis for disease detection, software for surgical planning, algorithms for speech production and auditory perception, and signal extraction for hearing aids.
Workpackage 7
Connected research and medicine (CoReMed)
This platform provides access to connected devices for research and clinical practices within reConnect. It aims to offer digital tools for multimodal data collection to ensure effective diagnosis and therapeutic intervention with strict data security.
